Fig. 6. Summary to illustrate the role of neurons in the mPFC in social buffering and the mechanism in reducing the fear response. Decreased pyramidal neuronal activity in pair-exposed rats produces a decreased fear response. Differential oxytocin-mediated interneuronal activity would produce a social buffering action. Latency, step-through latency into black compartment; Preference, black compartment preference; Entry #, number of entries into black compartment; IR, input resistance; PN, pyramidal neuron; IN, interneuron; # AP, number of action potential spike; OT, oxytocin.
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