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Fig. 5. Corti.Pups exert hyperactive and anxiolytic behaviors in EPM test. (A) Example traces of locomotor activities of pups in the open arms of EPM. (B, C) Changes of spent time and movement distance in the open arms during 5 days of EPM test. Corti.Pups showed longer spent time and movement distance with higher variation in the open arms, compared with Nor.Pups. (D) Changes of the extremity. During the test, attempts to touch the end of open arms was more frequently observed in Corti.Pups, demonstrating the impulsivity and anxiolytic behaviors. (E) Changes of locomotor velocity in the open arms. Data indicate the meanĀ±S.E. *p<0.05, **p<0.01.
Exp Neurobiol 2021;30:87~100 https://doi.org/10.5607/en20057
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