Fig. 6. Corti.Pups show hyperactive behaviors with cognitive declines in MWM test. (A) Example traces of swimming activities of pups in MWM test. (B, C) Changes of escape time and travel distance for 5 trial days of the test. Longer time and distance were observed in Corti.Pups during the initial three days, compared with Nor.Pups. However, similar with Nor.Pups, Corti.Pups rapidly found the hidden platform on the 4th and 5th test days, showing delayed cognitive function in the learning task. (D) Changes of swimming velocity. Data indicate the mean±S.E. *p<0.05, **p<0.01.
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