Fig. 1. miR-20b was significantly downregulated after I/R both in vitro and in vivo. (A-C) Neurons were treated with OGD/R (2 h/24 h). (A) Cell viability was evaluated by MTT assay. (C) Apoptotic rate was measured by flow cytometry. (C) The mRNA level of miR-20b was detected by qRT-PCR. (D-F) Rats were treated with MCAO/R. (D) Neurobehavioral scores. (E) The representative images of brains tissues and infarct volume. (F) The mRNA level of miR-20b in brain tissues was evaluated by qRT-PCR. **p<0.01.
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