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Fig. 4. Hippo signaling pathway and neuroactive ligand-receptor interaction pathway are altered in DMD patients with ID. (A) KEGG pathway enrichment scatterplots show upregulated and downregulated pathways; x axes indicate the rich factor, the ratio of the number of genes involved in a certain pathway to the total number of differentially expressed genes. The y axes indicate the signaling pathways. The color and the size of each dot represent the range of p values and the number of DEGs mapped to the indicated pathways, respectively. Pathways with the highest level of alterations are indicated with arrows. (B) Venn diagrams showing the numbers of overlapping genes among participants in the two pathways.
Exp Neurobiol 2021;30:263~274
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