Fig. 5. Chronic stress increased the excitatory input, but not the inhibitory input, to POMC neurons. (A) Schematic diagram for whole cell patch-clamp for EPSCs. (B) Representative traces of sEPSC in POMC neurons from CON and CRS mice. Right traces were enlarging to the gray box in left traces. (C) The frequency of sEPSC in POMC neurons was decreased by chronic stress (*p=0.0229). (D) The amplitude of sEPSCs. (E) The area of sEPSCs. (F) The rise time of sEPSCs. (G) The decay time of sEPSCs. (H) Schematic diagram for whole cell patch-clamp for sIPSCs. (I) Representative traces of sIPSCs in POMC neurons from CON and CRS group. The traces in gray box were enlarged to right traces. (J) The frequency of sIPSC. (K) The amplitude of sIPSC. (L) The area of sIPSCs. (M) The rise time of sIPSCs. (N) The decay time of sIPSCs. The data for sEPSC are from CON (22 neurons from 9 mice) and CRS (19 neurons from 10 mice). The data for sIPSCs are from CON (10 neurons from 3 mice) and CRS (9 neurons from 3 mice).
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