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Fig. 7. HO2 treatment increased the reduced neurogenesis in the hippocampus of CRST mice. (A, B) Photomicrographs showing anti-Ki67-stained cells in the dentate gyrus (A) of control, CRST mice, CRST mice treated with HO2 (100% O2) at 2.0 ATA for 1 h daily for 14 days and CRST mice treated with imipramine (IMI). Quantification of anti-Ki67-positive cells in the dentate gyrus. Scale bar; 200 µm. (C, D) Photomicrographs showing anti-doublecortin (DCX)-stained cells in the dentate gyrus (A) of control, CRST mice, CRST mice treated with HO2 (100% O2) at 2.0 ATA for 1 h daily for 14 days and CRST mice treated with imipramine (IMI). Quantification of anti-DCX-positive cells in the dentate gyrus. Scale bar; 200 µm. Mean±SEM (n=7~8 animals per group). *,**difference between indicated group. *p<0.05, **p<0.01 (one-way ANOVA and Newman-Keuls post hoc test).
Exp Neurobiol 2021;30:415~429 https://doi.org/10.5607/en21029
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