Experimental Neurobiology

Fluorescence intensity of SOX2, Beclin 1, and colocalized SOX2-Beclin 1 in the Sal, LPS and LPS+3MA groups

Fluorescence		Sal	LPS	LPS+3MA
SOX2	Area	4,889±201.0	7,474±536.2*	4,778±470.6^#
	Raw intensity (RawIntDen)	786,510±40,797	1.147×10⁶±75,934*	876,754±40,754^#
Beclin 1	Area	2,387±460.1	12,450±2,385*	2,936±1,012^#
	Raw intensity (RawIntDen)	491,331±91,594	2.567×10⁶±490,572*	608,749±219,862^#
SOX2+Beclin 1	Area	705±60.68	2,371±419.9**	229±79.95^##
	Raw intensity (RawIntDen)	142,614±8554	426,168±63,119**	45,812±18,126^##

Values are the mean±SEM, n=3 animals per experimental group. *p<0.05, **p<0.01 vs. Sal group and ^#p<0.05, ^##p<0.01 vs. LPS group in the post hoc Tukey’s multiple range tests. SOX2: SRY-Box Transcription Factor 2. Sal: saline infusion, LPS: LPS peritoneal infusion (IP) with saline icv infusion, LPS+3MA: LPS (IP) with 3MA (icv). icv: intracerebroventricular infusion. 3MA: 3-Methyladenine.

Exp Neurobiol 2022;31:307~323 https://doi.org/10.5607/en22005