Experimental Neurobiology

Fluorescence intensity of SOX2, p-S6k, and colocalized SOX2-p-S6k in the Sal, LPS and LPS+3MA groups

Fluorescence		Sal	LPS	LPS+3MA
SOX2	Area	5,228±140.2	6,877±497.9*	4,141±307.3^##
	Raw intensity (RawIntDen)	1.051×10⁶±22368	1.516×10⁶±160,491*	837,862±19,242^##
p-S6k	Area	15,923±872.4	3,222±574.2***	9,445±837.7^###
	Raw intensity (RawIntDen)	3.153×106±134761	692,404±136992***	2.183×10⁶±302,913^##
SOX2+p-S6k	Area	2,887±211.0	465±277.8*	3,614±561.3^##
	Raw intensity (RawIntDen)	635,061±26,374	99,761±61,819*	585,605±162,954^#

Values are the mean±SEM, n=3 animals per experimental group. *p<0.05, ***p<0.001 vs. Sal group and ^#p<0.05, ^##p<0.01, ^###p<0.001 vs. LPS group in the post hoc Tukey’s multiple range tests. SOX2: SRY-Box Transcription Factor 2. Sal: saline infusion, LPS: LPS peritoneal infusion (IP) with saline icv infusion, LPS+3MA: LPS (IP) with 3MA (icv). icv: intracerebroventricular infusion. 3MA: 3-Methyladenine.

Exp Neurobiol 2022;31:307~323 https://doi.org/10.5607/en22005