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Fig. 3. A decrease in the number of Ki67-positive cells and DCX-positive cells in the dentate gyrus of LPSIP animals was prevented by icv infusion of 3MA. (A) Representative images and total number counts of Ki67-positive cells and (B) newborn neurons generated from progenitor cells (DCX-positive cells) in the subgranular zone of the dentate gyrus. Values are the mean±SEM (n=8 to 12 animals per experimental group). *p<0.05, ***p<0.001 in the post hoc Tukey's multiple range test. Sal: saline infusion, LPS: LPS (IP) with saline (icv), L+3MA: LPS (IP) with 3MA (icv). Scale bar: 50 µm. DCX: doublecortin.
Exp Neurobiol 2022;31:307~323
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