Fig. 4. The decreased protein expression of mTOR signaling in the hippocampus of animals treated with LPS was prevented by icv infusion of 3MA. Representative gels (inset) and densitometric analysis of the Western blot results showing changes in the expression of (A) mTOR, (B) phospho(p)-mTOR and the (C) p-mTOR/mTOR ratio. Values are the mean±SEM, n=10 to 12 animals per experimental group. *p<0.05, *** p< 0.001 in the post hoc Tukey’s multiple range tests. Sal: saline infusion, LPS: LPS IP infusion with saline (icv), LPS+3MA: LPS (IP) with 3MA (icv).
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