Fig. 5. PLCγ1 in CA2 hippocampus is critical for visuosocial preference, but not avoidance, memory. (A) Summary bar graph of visuosocial avoidance memory test with C57BL/6 photo (n=5, 10, 6, and 10). Two-way ANOVA, p>0.05. 1st vs 2nd lanes, *p<0.05; 3rd vs 4th lanes, **p<0.01. (B) Summary bar graph of visuosocial avoidance memory test with a neutral cue (n=6 and 6). Student’s t-test, ns, not significant. (C) Summary bar graph of visuosocial preference memory test with PLCγ1f/f (control) and PLCγ1f/f×RGS14-cre (PLCγ1 cKO) mice (n=19 and 13). Student’s t-test, *p<0.05. (D) Summary bar graph of visuosocial preference memory test with a neutral cue (n=6 and 4). Student’s t-test, ns, not significant. (E) Comparison of entering frequency in open tunnel session between Day 1 (Before foot shock or DAMGO) and Day 2 (After foot shock or DAMGO) in control and PLCγ1 cKO mice. Two-way ANOVA, ns, not significant. Results are mean±SEM.
© Exp Neurobiol
