Significant change in white matter tracts between MDD patients and HC
| Tract of interest | MDD (n=101) | HC (n=99) | MDD vs. HC | |||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | F | p-value | |
| FA | ||||||
| Left ILF | 0.48 | 0.02 | 0.49 | 0.03 | 12.247 | 0.001 |
The F and p values were obtained using one-way analysis of covariance (ANCOVA) with the adjustment for age, sex, and education level as covariates.
MDD, patients with major depressive disorder; HC, healthy control participants; SD, standard deviation; ILF, inferior longitudinal fasciculus.
Bonferroni correction was applied: p<0.05/72=0.00069.