Fig. 4. Contribution of the dopamine receptors to the TA-LTD. (Aa) The PP-LFS to the TA-CA1 synapses induced the LTP of the TA-EPSC amplitude under the SCH23390. Top, representative EPSCs recorded before the induction of the PP-LFS (a, Control) and 25~30 min after the PP-LFS (b, pPP-LFS). (Ab) The PP-LFS to the TA-CA1 synapses did not change the PPR of the TA-CA1 synapses under the SCH23390. (Ba) The PP-LFS of the SLM induced the LTP of the TA-EPSC amplitude under the sulpiride. Top, representative EPSCs recorded before the induction of the PP-LFS (a, Control) and 25~30 min after the PP-LFS (b, pPP-LFS). (Bb) The PP-LFS to the TA-CA1 synapses did not change the PPR of the TA-CA1 synapses under the sulpiride. (Ca) The PP-LFS of the SLM under the anti-DARs (co-application of SCH23390 and sulpiride) transiently increased the TA-EPSC; however, the increase was not sustained. Top, representative EPSCs recorded before the induction of the PP-LFS (a, Control) and 25~30 min after the PP-LFS (b, pPP-LFS). (Bb) The PP-LFS to the TA-CA1 synapses did not change the PPR of the TA-CA1 synapses under the anti-DARs. (Da) The SC-LFS at the Schaffer collateral (SC) under the anti-DARs (co-application of SCH23390 and sulpiride) induced the LTD of the TA-EPSC. Top, representative EPSCs recorded before the induction of the PP-LFS (a, Control) and 25~30 min after the PP-LFS (b, pPP-LFS). (Db) The PP-LFS to the TA-CA1 synapses did not change the PPR of the SC-CA1 synapses under the anti-DARs.
© Exp Neurobiol
