Fig. 4. STZ (injected via the ICM route)-induced AD pathology in the hippocampus of cynomolgus monkeys. (A) A schematic diagram of the experimental schedule. The expression levels of (B) NeuN, (C) Synaptophysin and PSD95, (D) p-Tau(S262), and (E) p-Tau(T181) and p-Tau(S396) with equal amount protein sample (15 μg) of hippocampus in vehicle- or STZ-injected cynomolgus monkeys were determined using western blotting analysis. * denotes p<0.05, ** denotes p<0.01, and *** denotes p<0.001.
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