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Fig. 5. Migratory effect of placental extract in RSC96 (Schwann cell line) using the wound healing assay. PE treatment has significantly increased the relative wound closure rate (A and B; t-test, *p<0.05, mean±SD) compared to the control group. Migration-related protein extracellular signal-regulated kinase (ERK) levels measured using immunoblot analysis to confirm the effect at the molecular level. The expression of p-ERK is increased in RSC96 treated with 2 mg/ml of PE (C and D; t-test, *p<0.05, mean±SD). Thus, the results suggest that PE improved the migration of RSC96 cells.
Exp Neurobiol 2022;31:419~430
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