Fig. 1. Distribution of CpG probes in a cellular model of PD. (A) Manhattan plot of negative logarithm p values plotted against different chromosome positions. The grey line indicates a suggestive threshold, p=1×10-3, while the red line specifies a genome-wide significant threshold p=1×10-5. (B) Volcano plot of genome wide DNA methylation of 6-OHDA on differentiated human neuroblastoma cells. The x-axis shows log2 (fold change) values and the y axis plots the negative logarithm p values.
© Exp Neurobiol
