Fig. 4. PPI network and overexpressed MCODE module regulated by 6-OHDA. (A) PPI visualized using MCODE algorithm where neighborhood densely connected DMRs were identified from clustered enrichment ontology terms. (B) MCODE1 consists of 3 genes, including ITPR1, GNG7, AKT1; MCODE2 consists of 3 genes, BRD9, ARID1A and ARID1B; MCODE3 consists of 3 genes, including MAPK1, GAK and ALK. (C) Description and p values of each MCODE network according to GO enrichment analysis.
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