Fig. 5. The synchronization and functional connectivity of cortical network in SD and GA mice. (A) Raster plots depicting changes in activity (ΔF/F) over time for a representative correlation matrix quantifying network synchronization between each cell and every other. (B) Representative correlation matrices quantifying functional connectivity between each cell and every other spine. (C, D) The network synchronization and mean cell-cell correlation during the whole experiment. n=42 cells in 6 SD mice, n=95 cells in 5 GA-treated mice. All data are shown as mean±SEM. ns, not significant, two-way ANOVA with Bonferroni correction. SD: SD+Saline. GA: SD+GA. (E) The network synchronization in SD 24 h, p=0.923; SD 48 h, p=0.744 and SD 72 h, 0.958. n=6 mice in SD+Saline group, n=5 mice in SD+GA mice. (F) The functional connectivity of cortical network. SD 24 h, p=0.6; SD 48 h, p=0.569 and SD 72 h, p= 0.872. n=6 mice in SD+Saline group, n=5 mice in SD+GA group. All data are shown as mean±SEM. ns, not significant, two-tailed unpaired t-test.
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