Intrinsic properties of layer 2/3 and layer 5 pyramidal neurons in the prelimbic cortex
| Intrinsic property | Prelimbic cortex | ||||||
|---|---|---|---|---|---|---|---|
| Layer 2/3 pyramidal neuron | Layer 5 pyramidal neuron | ||||||
| sham | tBCCAO | p value | sham | tBCCAO | p value | ||
| AP threshold (mV) | -27.73±1.48 | -25.63±1.86 | 0.368 | -30.34±0.95 | -29.04±0.96 | 0.340 | |
| AP amplitude (mV) | 86.04±0.98 | 84.20±1.46 | 0.301 | 84.77±1.14 | 86.13±1.25 | 0.426 | |
| FWHM (ms) | 0.97±0.04 | 0.83±0.03 | 0.015 |
0.900±0.04 | 0.83±0.02 | 0.106 | |
| AP upstroke (V/s) | 459.31±25.62 | 507.43±32.14 | 0.249 | 420.16±14.71 | 465.38±16.39 | 0.046 |
|
| AP downstroke (V/s) | -79.96±3.63 | -92.89±4.62 | 0.036 |
-86.12±4.16 | -107.75±12.56 | 0.109 | |
| fAHP (mV) | 11.06±0.99 | 11.34±0.67 | 0.822 | 9.35±0.65 | 10.04±0.56 | 0.426 | |
| mAHP (mV) | 0.93±0.32 | 0.87±0.24 | 0.890 | 3.18±0.25 | 4.05±0.34 | 0.044 |
|
| RMP (mV) | -66.52±2.22 | -66.64±2.16 | 0.973 | -62.63±1.37 | -61.91±1.23 | 0.725 | |
Layer 2/3 pyramidal neurons (sham=14, tBCCAO=13), layer 5 pyramidal neurons (sham=23, tBCCAO=23). *p<0.05.