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Perspective

Exp Neurobiol 2017; 26(6): 319-320

Published online December 31, 2017

https://doi.org/10.5607/en.2017.26.6.319

© The Korean Society for Brain and Neural Sciences

Hopping from One Cell to Another: Huntington's Disease Propagates

Sang Myun Park*

Department of Pharmacology, Ajou University School of Medicine, Suwon 16499, Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, Suwon 16499, BK21 plus program, Department of Biological Sciences, Ajou University School of Medicine, Suwon 16499, Korea

Correspondence to: *To whom correspondence should be addressed.
TEL: 82-31-219-5063, FAX: 82-31-219-5069
e-mail: sangmyun@ajou.ac.kr

References

  1. Kim DK, Cho KW, Ahn WJ, Perez-Acuña D, Jeong H, Lee HJ, Lee SJ. Cell-to-cell transmission of polyglutamine Aggregates in C. elegans. Exp Neurobiol
  2. Agorogiannis EI, Agorogiannis GI, Papadimitriou A, Hadjigeorgiou GM. Protein misfolding in neurodegenerative diseases. Neuropathol Appl Neurobiol 2004;30:215-224.
    Pubmed
  3. Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E. Cell-to-cell transmission of non-prion protein aggregates. Nat Rev Neurol 2010;6:702-706.
    Pubmed
  4. Stopschinski BE, Diamond MI. The prion model for progression and diversity of neurodegenerative diseases. Lancet Neurol 2017;16:323-332.
    Pubmed
  5. Pecho-Vrieseling E, Rieker C, Fuchs S, Bleckmann D, Esposito MS, Botta P, Goldstein C, Bernhard M, Galimberti I, Müller M, Lüthi A, Arber S, Bouwmeester T, van der Putten H, Di Giorgio FP. Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons. Nat Neurosci 2014;17:1064-1072.
    Pubmed
  6. Tak H, Haque MM, Kim MJ, Lee JH, Baik JH, Kim Y, Kim DJ, Grailhe R, Kim YK. Bimolecular fluorescence complementation; lighting-up tau-tau interaction in living cells. PLoS One 2013;8:e81682.
    Pubmed
  7. Outeiro TF, Putcha P, Tetzlaff JE, Spoelgen R, Koker M, Carvalho F, Hyman BT, McLean PJ. Formation of toxic oligomeric alpha-synuclein species in living cells. PLoS One 2008;3:e1867.
    Pubmed
  8. Nussbaum-Krammer CI, Morimoto RI. Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases. Dis Model Mech 2014;7:31-39.
    Pubmed
  9. Surmeier DJ, Obeso JA, Halliday GM. Parkinson's disease is not simply a prion disorder. J Neurosci 2017;37:9799-9807.
    Pubmed
  10. Brundin P, Melki R. Prying into the prion hypothesis for Parkinson's disease. J Neurosci 2017;37:9808-9818.
    Pubmed
  11. Kim DK, Lim HS, Kawasaki I, Shim YH, Vaikath NN, El-Agnaf OM, Lee HJ, Lee SJ. Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function. Autophagy 2016;12:1849-1863.
    Pubmed