Highlights
  • Review Article | February 29, 2024

    This article provides an review of autoimmune encephalitis (AIE) and its underlying pathological mechanisms. AIE is a rare condition characterized by inflammation in the brain parenchyma, often triggered by autoimmune attacks on specific neuronal epitopes. The article emphasizes the need for early diagnosis and effective treatment while highlighting the challenges in diagnosing AIE and the recognition of CD8+ lymphocytic encephalitis.

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    This article provides an review of autoimmune encephalitis (AIE) and its underlying pathological mechanisms. AIE is a rare condition characterized by inflammation in the brain parenchyma, often triggered by autoimmune attacks on specific neuronal epitopes. The article emphasizes the need for early diagnosis and effective treatment while highlighting the challenges in diagnosing AIE and the recognition of CD8+ lymphocytic encephalitis.
    Yu-Mi Shim, Seong-Ik Kim, So Dug Lim et al.
  • Original Article | February 29, 2024

    There was reduced medulla volume in patients with panic disorder. This may be related to panic disorder pathophysiology, given the medulla’s role in fear and autonomic function.

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    There was reduced medulla volume in patients with panic disorder. This may be related to panic disorder pathophysiology, given the medulla’s role in fear and autonomic function.
    Hye-Min Kim, Chanmi Kang, Boram Chae et al.
  • Original Article | February 29, 2024

    There is a need to explore noninvasive treatment after neonatal hypoxic ischemia. Intranasal administration of a 7-day BDNF treatment in PND 7 neonatal mice, resulted in cognitive rescue and neural plasticity.

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    There is a need to explore noninvasive treatment after neonatal hypoxic ischemia. Intranasal administration of a 7-day BDNF treatment in PND 7 neonatal mice, resulted in cognitive rescue and neural plasticity.
    Serena-Kaye Sims, Madelynne Saddow, Lilly McGonegal and Catrina Sims-Robinson
  • Original Article | February 29, 2024

    Endogenous LRRK2 was significantly increased in stroke models. LRRK2 inhibition has neuroprotective effects in that. LRRK2 targeted therapies could be helpful for treating stroke

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    Endogenous LRRK2 was significantly increased in stroke models. LRRK2 inhibition has neuroprotective effects in that. LRRK2 targeted therapies could be helpful for treating stroke
    Jeong-Ah Hwang, Seung Kyu Choi, Seong Hwan Kim and Dong Woon Kim
Vol.33 No.1 | February 29, 2024

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KSBNS-APSN 2024 en Experimental Neurobiology in SCIe As of August 2017 Covered from 2015
2019 Impact Factor 2.370. 2020 Impact Factor 3.261. 2021 Impact Factor 3.800. 2022 Impact Factor 2.4. KSBNS-APSN 2024

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We propose extending the study of LRRK2, traditionally investigated in the context of Parkinson's Disease (PD), to stroke models, thereby suggesting LRRK2 inhibitors as a novel alternative for stroke treatment. In our Rose Bengal model, the induction of stroke unveiled hyperphosphorylation and puncta formation of LRRK2. This introduces a new avenue for further research into the underlying mechanisms associated with LRRK2 in stroke onset.