Highlights
  • Review Article | August 31, 2022

    The medial prefrontal cortex governs the expression, storage, and extinction of fear memory. This review summarizes recent publications on how neuronal plasticity events in subregions of the medial prefrontal cortex underlie storing and extinction of fear memory.

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    The medial prefrontal cortex governs the expression, storage, and extinction of fear memory. This review summarizes recent publications on how neuronal plasticity events in subregions of the medial prefrontal cortex underlie storing and extinction of fear memory.
    Yongmin Sung and Bong-Kiun Kaang
  • Review Article | August 31, 2022

    Autophagy has been reported to protect against inner ear hair cell loss. This review summarizes the use of autophagy to treat tinnitus induced by hair cell loss.

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    Autophagy has been reported to protect against inner ear hair cell loss. This review summarizes the use of autophagy to treat tinnitus induced by hair cell loss.
    Karthikeyan A Vijayakumar, Gwang-Won Cho, Nagarajan Maharajan and Chul Ho Jang
  • Original Article | August 31, 2022

    IKL in rat cochlear afferent nerve fiber dendrite is conducted via Kv1.1and Kv1.2, with a minor contribution from Kv7.2 and other as yet unidentified channels.

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    IKL in rat cochlear afferent nerve fiber dendrite is conducted via Kv1.1and Kv1.2, with a minor contribution from Kv7.2 and other as yet unidentified channels.
    Kushal Sharma, Kwon Woo Kang, Young-Woo Seo et al.
  • Original Article | August 31, 2022

    This is the first report that Cephalotocin, a newly synthesized octopus peptide, has an effect on ameliorating stress with reduced hippocampal synaptic glutamate transmission.

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    This is the first report that Cephalotocin, a newly synthesized octopus peptide, has an effect on ameliorating stress with reduced hippocampal synaptic glutamate transmission.
    Ye-Ji Kim, Seonmi Jo, Seung-Hyun Jung and Dong Ho Woo
  • Case Report | August 31, 2022

    Blood-brain barrier (BBB) is a semi-permeable component that protects the CNS from viral infection. While intraventricular brain tumor likely allows the structure of the BBB to remain undamaged, preventing the passage of SARS-CoV-2 and other pro-inflammatory molecules A), the presence of tumors that probably disrupt the BBB, in this case, a petroclival meningioma, allows the free passage of SARS-CoV-2 virus and let the free transit of pro-inflammatory molecules to the CNS or the activation of the microglia B), which leads to an exacerbated immune response mediated by IL-13, IFN-γ, and IL-2.

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    Blood-brain barrier (BBB) is a semi-permeable component that protects the CNS from viral infection. While intraventricular brain tumor likely allows the structure of the BBB to remain undamaged, preventing the passage of SARS-CoV-2 and other pro-inflammatory molecules A), the presence of tumors that probably disrupt the BBB, in this case, a petroclival meningioma, allows the free passage of SARS-CoV-2 virus and let the free transit of pro-inflammatory molecules to the CNS or the activation of the microglia B), which leads to an exacerbated immune response mediated by IL-13, IFN-γ, and IL-2.
    Jahir Rodríguez-Morales, Sebastián Guartazaca-Guerrero, Salma A. Rizo-Téllez et al.
Vol.31 No.4 | August 31, 2022

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Low-voltage activating K+ channels are expressed in cochlear afferent nerve fiber dendrites

Immunolabeling of Kv1.2 subunit in whole-mount rat cochlear preparations. Kv1.2 immunoreactivity (red) is present in the majority of Na+, K+, ATPase-positive (NKA, green) dendritic segments of cochlear afferent nerve fibers (ANF) contacting calretinin-positive (Blue) inner hair cells.