Highlights
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Original Article | June 30, 2021
The
Show moreGli1 promoter is active in the external granule cell layer (EGL) and Bergman glia (BGs) in the developing cerebellum. Administration of tamoxifen during early postnatal days (P4-7) induces expression of Cre recombinase driven by Gli1 promoter in EGL and BGs whereas during late postnatal days (P19-22) tamoxifen induces Cre recombinase expression in only BGs. This system is suggested for conditional knockout of genes of interest from cerebellar granule cell neurons (GCNs) and/or BGs.
TheGli1 promoter is active in the external granule cell layer (EGL) and Bergman glia (BGs) in the developing cerebellum. Administration of tamoxifen during early postnatal days (P4-7) induces expression of Cre recombinase driven by Gli1 promoter in EGL and BGs whereas during late postnatal days (P19-22) tamoxifen induces Cre recombinase expression in only BGs. This system is suggested for conditional knockout of genes of interest from cerebellar granule cell neurons (GCNs) and/or BGs.Jung-Mi Choi, Rakshya Acharya, Subash Marasini et al. -
Short Communication | June 30, 2021
An et al. demonstrate that the differential proximity of astrocytic Best1 at the inhibitory and excitatory synapse in APP/PS1 and MAOB KO mice by using Lattice SIM super-resolution microscopy.
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An et al. demonstrate that the differential proximity of astrocytic Best1 at the inhibitory and excitatory synapse in APP/PS1 and MAOB KO mice by using Lattice SIM super-resolution microscopy.Heeyoung An, Wuhyun Koh, SeungHee Kang et al. -
Original Article | June 30, 2021
An et al. demonstrate that adenovirus injection into SNpc causes severe reactive astrogliosis and exacerbates the A53T-α-synuclein-mediated PD pathology.
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An et al. demonstrate that adenovirus injection into SNpc causes severe reactive astrogliosis and exacerbates the A53T-α-synuclein-mediated PD pathology.Heeyoung An, Hyowon Lee, Seulkee Yang et al. -
Original Article | June 30, 2021
Ciliogenesis is not directly regulated by LRRK2 kinase activity. Comparison of ciliogenesis in various G2019S /WT pairs with different genetic backgrounds exhibits different patterns, suggesting its genetic specificity.
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Ciliogenesis is not directly regulated by LRRK2 kinase activity. Comparison of ciliogenesis in various G2019S /WT pairs with different genetic backgrounds exhibits different patterns, suggesting its genetic specificity.Hyejung Kim, Hyuna Sim, Joo-Eun Lee et al.
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News
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Here is the winner of the 2021 EN Best Article Awards announced at the KSBNS 2021 Virtual Conference held on May 20~21, 2021. Congratulations to Dr. Joungha Won...…
Show more2021-05-28 -
Here are the winners of the 2020 EN Best Article Awards announced at the KSBNS 2020 Virtual Conference held onNovember 16~17, 2020. - Review Article Congratulat...…
Show more2020-11-18 -
기초과학연구원 인지및사회성연구단 이창준 단장과 동(同)소속 한영은 박사가 2020년 한국과학기술단체총연합회(KOFST, 이...…
Show more2020-06-30
