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Original Article | June 30, 2023
The 6-OHDA-induced cytotoxicity resulted in significant DNA methylation changes on differentiated neuroblastoma cells with three DMRs closely associated with neurological diseases.
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The 6-OHDA-induced cytotoxicity resulted in significant DNA methylation changes on differentiated neuroblastoma cells with three DMRs closely associated with neurological diseases.Kasthuri Bai Magalingam, Sushela Devi Somanath and Ammu Kutty Radhakrishnan -
Original Article | June 30, 2023
Splice variants of ANO2 expressed in the brain have calcium-dependent channel kinetics and structures that contribute to the diversity of these neurons.
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Splice variants of ANO2 expressed in the brain have calcium-dependent channel kinetics and structures that contribute to the diversity of these neurons.Dongsu Lee, Hocheol Lim, Jungryun Lee et al. -
Original Article | June 30, 2023
We developed an
Show morein vitro model using A53T α-syn-EGFP overexpressing SH-SY5Y cells and preformed recombinant α-syn fibrils and validated its usefulness for high-throughput screening of potential therapeutic targets. This simple and efficientin vitro model system can be used for high-throughput screening to discover new targets for inhibiting α-syn propagation.
We developed anin vitro model using A53T α-syn-EGFP overexpressing SH-SY5Y cells and preformed recombinant α-syn fibrils and validated its usefulness for high-throughput screening of potential therapeutic targets. This simple and efficientin vitro model system can be used for high-throughput screening to discover new targets for inhibiting α-syn propagation.Beom Jin Kim, Hye Rin Noh, Hyongjun Jeon and Sang Myun Park -
Original Article | June 30, 2023
This study proposes a novel biomimetic model to describe long-term spiking adaptation of slowly adapting type-I tactile afferent neurons in response to sustained mechanical touch.
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This study proposes a novel biomimetic model to describe long-term spiking adaptation of slowly adapting type-I tactile afferent neurons in response to sustained mechanical touch.Jaehun Kim, Young In Choi, Jeong-woo Sohn et al. -
Original Article | June 30, 2023
We developed a machine learning-assisted method for quantitative and fine spatial mapping of the intracortical axonal plasticity following a focal stroke.
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We developed a machine learning-assisted method for quantitative and fine spatial mapping of the intracortical axonal plasticity following a focal stroke.Hyung Soon Kim, Hyo Gyeong Seo, Jong Ho Jhee et al. -
Original Article | June 30, 2023
Although counting TH+ neurons is essential for the preclinical study of Parkinson's disease, it requires a laborious and time-consuming manual procedure. Here, we developed a CNN-based TH+ neuron detection algorithm and an easy-to-use GUI for unbiased and efficient analysis of TH+ neurons. The proposed method offers the superior performance and accessibility over the existing methods.
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Although counting TH+ neurons is essential for the preclinical study of Parkinson's disease, it requires a laborious and time-consuming manual procedure. Here, we developed a CNN-based TH+ neuron detection algorithm and an easy-to-use GUI for unbiased and efficient analysis of TH+ neurons. The proposed method offers the superior performance and accessibility over the existing methods.Doyun Kim, Myeong Seong Bak, Haney Park et al.
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Highly Cited Papers
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Review Article | December 30, 2015Geon Ha Kim, Jieun E. Kim, Sandy Jeong Rhie and Sujung Yoon
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Review Article | March 30, 2013Onyou Hwang*
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Review Article | June 30, 2015Hyo Eun Moon and Sun Ha Paek
News
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한국과총에서 주관하는 「2023년 제33회 과학기술우수논문상」에 우리 학회 학술지 EN에 발간된 논문이 선정되었습니다.&n...…
Show more2023-06-23 -
Here is the winner of the 2021 EN Best Article Awards announced at the KSBNS 2021 Virtual Conference held on May 20~21, 2021. Congratulations to Dr. Joungha Won...…
Show more2021-05-28 -
Here are the winners of the 2020 EN Best Article Awards announced at the KSBNS 2020 Virtual Conference held onNovember 16~17, 2020. - Review Article Congratulat...…
Show more2020-11-18
