Articles
Article Tools
 View Full Text |
 Abstract |
 Article as PDF |
 Print this Article |
 Pubmed |
 PMC |
 PubReader |
 Export to Citation |
 Email Alerts |
 Open Access |
Share this article on :
Stats or Metrics
Article
Review Article
Exp Neurobiol 2014; 23(1): 45-52
Published online March 30, 2014
https://doi.org/10.5607/en.2014.23.1.45
© The Korean Society for Brain and Neural Sciences
Alzheimer’s Disease and Stem Cell Therapy
Sung S. Choi1#, Sang-Rae Lee2#, Seung U. Kim3 and Hong J. Lee1*
1Medical Research Institute, Chung-Ang University College of Medicine, Seoul 156-756, 2National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang 363-883, Korea, 3Division of Neurology, Department of Medicine, University of British Columbia, Vancouver 317-2194, Canada
Correspondence to: *To whom correspondence should be addressed.
TEL: 82-2-070-4623-7719, FAX: 82-2-070-4623-7719
e-mail: leehj71@gmail.com
#These authors are contributed equally.
Abstract
- Go to
- Abstract
The loss of neuronal cells in the central nervous system may occur in many neurodegenerative diseases. Alzheimer's disease is a common senile disease in people over 65 years, and it causes impairment characterized by the decline of mental function, including memory loss and cognitive impairment, and affects the quality of life of patients. However, the current therapeutic strategies against AD are only to relieve symptoms, but not to cure it. Because there are only a few therapeutic strategies against Alzheimer's disease, we need to understand the pathogenesis of this disease. Cell therapy may be a powerful tool for the treatment of Alzheimer's disease. This review will discuss the characteristics of Alzheimer's disease and various available therapeutic strategies.
Keywords: Alzheimer’s disease, stem cell-gene therapy, transplantation
